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Raising a puppy that is less than two pounds takes a special skill and desire. Most do not want to have “teacup” dogs, but occasionally we get one in a litter.
How Do You Vaccinate a Small Dog
Are vaccines safe for small dogs? Vaccines can be a big confusion. It is important not to “knock them down” with combination vaccines. Keep the number of viruses in the vaccine simple for success. Start with simplified vaccine antigens, then build gradually until they are old enough (and big enough) to handle the combination vaccines.
The ideal start weight to begin vaccination is over one pound but that can be seven to eight weeks and a little too late for Parvo. By six weeks of age, use a Parvo-only vaccination with an antihistamine and make sure they continue nursing. A tiny dog’s common response to viruses is to quit eating – one of the reasons to limit the virus vaccine to Parvo only!
Combination Vaccines for Small Dogs
Be careful with combinations and 5-way vaccines when the dog is less than two pounds. A Distemper/Parvo combination (Nobivac Puppy-DPv) is well tolerated and needs to be given by 10 weeks. The 12 and 16-week-old puppy can use the DPv booster or 5-way vaccine if desired. Continue to make sure they stay on their food!
Half-Dosing Injectable Vaccines: Don’t Do It
When it comes to giving a small dog injection, never half dose injectable vaccines. No studies have shown that splitting the vaccine is reliable – it results in uneven levels of antigens in each syringe. Instead of half-dosing combination vaccines, it is possible to reduce the number of antigens being put into their small bodies with a simplified vaccine. This means fewer antigens but maximum protection, and the whole vaccine is needed to successfully stimulate immunity. After completing that, it is possible to build on that protection with combination vaccines.
Intranasal Vaccines
When using intranasal vaccines, the most important thing to remember is to be gentle and keep the intranasal vaccine intranasal. Their tiny noses need to have a smaller volume of vaccine, so only use half of the liquid diluents to rehydrate the freeze-dried virus/bacteria. With less volume, you’ll be less likely to push the vaccine into the trachea and cause the puppy to cough. One easy method is to simply place the drops on the nose and let the puppy pull it in himself. By dripping it over the nose, you don’t force the vaccine at all. Intranasal vaccines are very safe and cause few issues if you keep this in mind.
Reactions to Vaccines
Reactions can happen with all vaccines. If they become listless and you suspect a reaction, don’t wait to treat – give them an antihistamine right away. Liquid children’s Benadryl is one option, giving 1 mg/lb for dogs – only a few drops. Some breeders will pre-medicate with Benadryl, giving it 30 minutes before vaccination to reduce the risk of reaction. This is a good habit – we don’t want to lose them for reactions that we know how to prevent. They do not react to intranasal vaccines, so we only pre-medicate for injectable vaccines.
Antibiotics and Vaccines
One more thing to keep in mind: never give intranasal vaccines while on antibiotics. Antibiotics will kill the modified live Bordetella in the vaccine, and you won’t get the immunity you need. Make sure your dogs are off any antibiotics for three days before and after the vaccine. A week after vaccination is best, but not always achievable.
The tiny dog demands special care and attention to thrive. But by simplifying their vaccines, you can consistently raise healthy dogs and make sure they’ll provide someone with a new best friend!
If you have more questions about small dog vaccinations, call a Revival Animal Care Specialist at 800.786.4751.
LEARN MORE:
How to Take Care of a Teacup Puppy | Raising Tiny Dogs
Tiny dogs demand special care and attention to thrive. Learn how to take care of a teacup Yorkie, Pomeranian, Chihuahua or other tiny dog.
Cat and Dog Vaccination Guide
Does my dog need a Lepto vaccine? Is feline leukemia vaccine necessary? Learn about recommended dog vaccines and recommended shots for cats.
Dog Vaccine FAQs
What vaccines do dogs need? What are core vaccines for dogs? Learn about annual dogs shots, modified live vs killed vaccines, and more.
How to Give A SubQ Injection Vaccination for Dogs and Cats
How can I give my dog shots at home? Do it yourself dog shots is an option for many pet owners. Watch how to give an injectable vaccination to your dog or cat.
Written by: Marty Greer, DVM
Director of Veterinary Services
Marty Greer, Doctor of Veterinary Medicine, has 40+ years’ experience in veterinary medicine, with special interests in canine reproduction and pediatrics. She received her Doctor of Veterinary Medicine from Iowa State University in 1981. She’s served as Revival’s Director of Veterinary Services since 2019. In 2023, Dr. Greer was named the Westminster Kennel Club Veterinarian of the Year.