Settle

• Equine endometritis treatment
• USDA approved
• Can help resolve certain uterine infections
• For use during natural breeding or artificial insemination
• For use with mares with endometritis

Prepare your mares for effective breeding with Settle^® equine endometritis treatment - a USDA-approved immunotherapeutic recommended to aid in treating equine endometritis.

Endometritis begins in mares and is an inflammation of the uterus to expel semen and bacteria after breeding. While not life-threatening, the condition, commonly caused by streptococcus zooepidemicus, significantly impacts the equine industry, affecting up to 43% of broodmares worldwide. Mares with persistent and post-breeding endometritis have an increased embryonic loss rate and a lower overall pregnancy rate than those without the condition.

If your mare has vulval or cervical discharge or uterine fluid accumulation, a single dose of Settle can help resolve the uterine infection, inflammation and discomfort before it leads to long-lasting issues.

Settle has been successfully administered at the following times:

• The diagnosis of uterine infection.
• The day after foaling.
• After retained placenta removal.
• During natural breeding or artificial insemination.
• Before shipping mares for breeding.

Instructions: Mix thoroughly before injecting. Use the entire contents when you first open the treatment. You can administer a 1.5ml dose of Settle directly into the uterus with a sterile catheter or via intravenous injection to the mare's jugular vein during early estrus. If needed, repeat the treatment at subsequent estrus periods.